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Today, I’m joined once again by neuroscientist Siobhan Mitchell for a conversation that will totally reframe how you think about creatine. Siobhan is here to break down why this simple supplement might actually be one of the most powerful and underappreciated tools for longevity, brain health, and overall resilience as we age.
Read MoreToday, I’m joined by Wade Lightheart, a true thought leader in the world of biohacking and co-founder of BiOptimizers. Wade has spent decades diving deep into the science of longevity—questioning what really moves the needle for our long-term health, and challenging some of the biggest assumptions in the wellness industry.
Read MoreToday, I’m diving solo into a topic that’s truly at the heart of everything I do: longevity—specifically, how to actually feel vibrant and strong as we age, not just rack up more years on the calendar. I break down the science behind aging, the real reasons why our repair systems start to slow down, and the practical ways we can take charge, starting right now.
Read MoreToday, I’m joined by Dan Pardi, a pioneering researcher who has dedicated years to understanding sleep, performance, and—the real focus of today’s conversation—the science of human energy. Dan unpacks how modern life is quietly draining our brain’s battery, and why brain energy, not just the march of time, could be the hidden driver of longevity.
Read MoreToday, I’m joined by Dr. Jill Crista, a pioneering voice in environmental medicine and a relentless detective when it comes to chronic, mysterious illness. In our conversation, Dr. Crista reveals how she uncovered the hidden world of mold and mycotoxins—not just as respiratory irritants, but as stealthy drivers of fatigue, brain fog, hormone disruption, and accelerated aging. She shares her early experiences working with “non-responders” in Lyme disease, and how uncovering toxic mold exposures transformed her entire understanding of whole-body health.
Read MoreToday, I’m mixing things up with a special episode that takes you on a tour through some of the most compelling moments from the past quarter. Rather than a typical interview or solo deep dive, I’ve curated standout clips from episodes that lit a fire under important longevity conversations and resonated deeply with both me and the team.
Read MoreFor years we've talked about longevity as if the answer is hiding in the next supplement, biomarker, or miracle molecule. But what if we've been looking at aging through far too narrow a lens? Today's guest, Dr. Marios Kyriazis, has spent decades challenging that idea by exploring aging through medicine, complexity science, cybernetics, and even philosophy.
Read MoreToday, I’m joined by the insightful Dr. Scott Sherr, a pioneer in health optimization and mitochondrial medicine. In our conversation, Dr. Sherr introduces his groundbreaking concept—the "sympathetic spiral of doom"—and explains why so many high performers end up burned out, frustrated, and feeling like their nervous systems are working against them.
Read MoreToday, I’m joined by Alex Kikel—a name that’s become synonymous with pushing the frontiers of biology, performance, and healing. Alex is the kind of person who, when told “there’s nothing more we can do,” responds with, “but what if that’s not true?” In our conversation, he shares the pivotal moments that made him question everything about the standard approach to health, including his personal story of reversing serious conditions when traditional solutions failed.
Read MoreToday, I’m joined once again by the innovative Ian Mitchell, a name familiar to anyone passionate about radical longevity, biohacking, and pushing the boundaries of human performance. In this conversation, Ian pulls back the curtain on the science and surprising applications of C60—known as the “buckyball” molecule—and why it’s become such a powerful tool for both peak performance and healthy aging.
Read MoreToday, I’m sitting down with the trailblazing Dr. Tyna Moore, a pioneer in reframing the conversation around GLP-1 medications. Instead of focusing solely on weight loss, Dr. Moore reveals how these powerful molecules can open a critical window to reset our health story—if we’re willing to harness that opportunity wisely.
Read MoreToday, I’m joined by the inspiring Dr. Anshul Gupta, a conventionally trained family physician who completely reimagined thyroid care after his own life and health hit a breaking point. Dr. Gupta shares how his battle with fatigue, weight gain, and relentless gut pain led him down a path beyond prescriptions, ultimately transforming his personal health and medical practice. Through functional medicine, he found a way out of his own struggle—and uncovered what so many thyroid patients are missing.
Read MoreToday, I’m joined by the incredibly insightful Donna Jackson Nakazawa, a science journalist and bestselling author whose work bridges the worlds of neuroscience, storytelling, and personal transformation. Donna has a unique gift for translating complex brain science into real-life strategies—and she’s not afraid to weave in her own powerful journey, from childhood trauma and autoimmune challenges to her fierce quest for hope and healing.
Read MoreToday, I’m joined by Kyal Van Der Leest, an innovative naturopath, nutritionist, and founder of LVLUP Health, whose formulas are changing the way we think about effective supplementation. Kyal’s journey is deeply personal: from caring for his mother through a long battle with cancer, to overcoming his own intense health struggles with mold illness. These experiences led him to push past superficial fixes and dig deep into what really works for healing and optimizing the body.
Read MoreToday, I'm joined by Dr. Taz Bhatia, a trailblazing integrative medicine physician, entrepreneur, and leading voice in women's health and longevity. In our conversation, Dr. Taz opens up about how her personal health challenges as a conventionally-trained MD led her to explore nutrition, Chinese medicine, and Ayurveda, inspiring her to reimagine what it means to truly care for the whole person.
Read MoreToday, I’m thrilled to welcome Dr. Nasha Winters back to the show for part two of our powerful conversation. As a trailblazer in integrative oncology and a passionate advocate for the “metabolic terrain” approach to health, Dr. Winters brings both deep expertise and a truly holistic perspective to the complex world of cancer and longevity. In this episode, she doesn’t just share concepts—she takes us into the heart of what it means to test, assess, and address our own health in real life, especially when we’re facing major diagnoses and difficult decisions.
Read MoreToday, I’m joined by the one and only Dr. Sandra Kaufmann—a true pioneer in the field of personalized longevity medicine and the creative force behind the Kaufman Protocol. In this episode, Sandra shares how a personal curiosity about why we age at the cellular level ultimately drew her away from a successful anesthesia career and into the world of building longevity strategies for real people. She opens up about the moment longevity became more than just an intellectual pursuit, and the surprising ways her work has grown into a global movement.
Read MoreToday, I’m joined by Todd Shipman, a curious mind who initially set out to debunk the world of quantum energy—and ended up completely rethinking how our biology, energy, and even our sense of connection really work. In this episode, Todd Shipman shares his surprising journey, from skeptic to quantum advocate, and walks us through what the quantum field is—using clear analogies that finally make sense of a subject that usually feels way too abstract.
Read MoreToday, I'm joined by Dr. Grace Liu, often known as the “Gut Goddess,” a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right—Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself.
Read MoreToday, I’m joined by Erin Ryan, my producer, for a special follow-up episode where we tackle your most pressing questions about bioregulators and peptides. After our wildly popular Bill Lawrence interview, the Longevity Podcast community sent in a wave of thoughtful queries—from cancer concerns to menopause, sourcing, and practical tips.
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