#472: Not Just Gym Creatine, This is LONGEVITY Creatine: Formulated To Support More Than Just Muscle | With Siobhan Mitchell
📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/
Today, I’m joined once again by neuroscientist Siobhan Mitchell for a conversation that will totally reframe how you think about creatine. Siobhan is here to break down why this simple supplement might actually be one of the most powerful and underappreciated tools for longevity, brain health, and overall resilience as we age.
We dive deep into why our brains are such energy hogs, what happens to our ATP reserves as we age, and how creatine goes far beyond the world of bodybuilders. Siobhan shares the latest research on creatine’s impact on cognition, sleep deprivation, muscle preservation (especially for women through menopause and men in andropause), injury recovery, and even its growing role in stacking for traumatic brain injury and mood support. And because this is the Longevity Podcast, we get into why creatine, when combined the right way with smart cofactors like citicoline and L-carnitine, could take mitochondrial and brain support to the next level.
So, if you’re curious about practical ways to close the energy gap as you get older, this episode will give you the science, the real-world tips, and the inspiration to look at creatine in a brand new light.
Head to MitoQ.com/nat and use code NAT10 to try it for yourself.
What We Discuss:
Welcome and podcast introduction ... 00:00:00
Creatine’s impact on brain and muscle energy ... 00:00:40
Creatine myths, bro culture, and broader benefits ... 00:01:30
Mitochondrial health, aging, and the Countdown initiative ... 00:02:19
Declining creatine intake with age and in women ... 00:09:40
Preventative power of creatine for muscle and mitochondria ... 00:14:05
Creatine’s role in fall risk, injury, and recovery ... 00:15:11
How to dose and titrate creatine ... 00:17:39
Benefits for older adults and cognitive health ... 00:18:49
Creatine and cognition: sleep deprivation, stress, mood ... 00:25:10
Special recommendations for menopausal and pregnant women ... 00:29:33
Choline, citicoline, and neuromuscular support ... 00:50:23
AKG, L-carnitine, and synergy for mitochondrial function ... 00:57:16
Study insights and future directions ... 01:00:46
Dosing, prepping, and best practices for creatine ... 01:10:31
Quickfire round and episode wrap up ... 01:15:52
Our Amazing Sponsors:
Countdown Insiders by Countdown — Join a community helping fund groundbreaking mitochondrial research while receiving exclusive events, science briefings, partner perks, and a voice in what Countdown does next. Get your first month free with code NATHALIE at joincountdown.org/membership.
Nature's Marvels Bioregulators by Profound Health - Natural bioregulators designed to support your body's own cellular communication and healthy aging, with targeted formulas for everything from brain and immune health to sleep and vitality. Visit https://profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order.
Grass-Fed Whey by Puori - A third-party tested, grass-fed whey protein delivering 21g of protein per serving, with every batch tested for over 200 contaminants and results available via a QR code for complete transparency. Head to puori.com/NAT and use code NAT to get 32% off your first subscription order, plus a free premium shaker bottle.
More from Nat:
For Transparency:
Some episodes of the Longevity With Nathalie Niddam podcast are supported by partners whose products or services may be discussed during the show. The host may receive compensation or earn a minor commission if you purchase through affiliate links at no extra cost to you. All opinions shared are those of the host and guests, based on personal experience and research, and do not necessarily represent the views of any sponsor. Sponsorships do not imply medical endorsement or approval by any healthcare provider featured on this podcast.