#395: Brain Fog, Anger, Detox Secrets & The Truth About Diet Sodas | Unlocking LIVER Longevity With Siggi Clavien

Today, I’m sitting down with the irrepressible Siggi Clavien, renowned biotech innovator and founder of De-liver-ance, a groundbreaking formula for liver health. Siggi’s story is deeply personal—motivated by the loss of loved ones to liver disease, he’s made it his life’s mission to demystify liver health and help others avoid the fate that touched his own family.

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#394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence

Today, I’m joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly with Professor Vladimir Khavinson—the scientist who discovered and developed bioregulator peptides—and has spent the last eight years leading some of the most exciting field research in this space.

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#393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso

Today, I'm joined by the incomparable Dr. Ted Achacoso—a true pioneer in shifting healthcare from “what’s wrong with you” to “what’s right with you.” Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can’t ignore, and how something as simple as a toxicity panel can completely change your health trajectory.

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#392: Biohacking the MIND: 78% Anxiety Remission, Vagus Nerve Secrets & The Mental Health Revolution | Zenbud’s Jon Hacker Unlocks REST

Today, I’m joined by the innovative Jon Hacker, whose name couldn’t be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mind. After growing up with severe OCD and witnessing the rising tide of global anxiety, he became obsessed with one question: Why are we all stuck in fight or flight, and what can we actually do about it?

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#391: Unlocking SCALP Health: The Biohack That Will Change Your Hair Forever With Nadine Artemis

Today, I’m joined by the incredible Nadine Artemis, a true pioneer in natural beauty and holistic health. Nadine is well known for bridging the gap between ancient wisdom and modern science, and in this episode, she completely redefines how we look at hair care—not just as a cosmetic routine, but as a form of biological reset. She shares how everything from stress to toxins and even your shower water can disrupt the delicate ecosystem of your scalp, and how her simple, nature-inspired rituals can help restore balance.

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#390: Muscle, Mitophagy, and Longevity: How Urolithin A Supports Healthy Aging and Athletic Performance With Brad Currier, PhD

Today, I’m joined by Dr. Brad Currier, chief scientist at Timeline Nutrition and an expert in the world of muscle and aging research. Brad is on the cutting edge of mitochondrial science, and in this episode, he helps us unravel the mysteries of why some 80-year-olds are still crushing it in the gym while others struggle to get up the stairs. We dive into his fascinating research on mitophagy—our bodies’ system for recycling dysfunctional mitochondria—and what it means for muscle health, strength, and vibrant aging.

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#389: How Migraines, Mitochondria Dysfunction, and Modern Lifestyles Impact Brain Health and Aging With Dr. Elena Gross

Today, I’m joined by the brilliant Dr. Elena Gross, a neuroscientist with an inspiring story and a relentless drive to solve the mysteries behind chronic migraines and brain health. Dr. Gross’s personal journey—enduring twenty days of migraine each month and navigating countless failed treatments—led her from crawling through the pain to founding Brain Ritual, a company reimagining brain fuel for longevity.

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#388: Nat’s Ultimate Gift Guide for Longevity Fans: Biohacks, Wellness Gadgets, and Black Friday Deals

Today, I’m sharing my go-to biohacking strategies and supplement stacks for leveling up your health and longevity. After years of testing the latest tech and science-backed interventions, I’ve curated smart bundles for better sleep, sharper focus, and lasting energy—perfect for your own routine or thoughtful holiday gifting. Go To NatNiddam.com/giftguide for all the holiday deals!

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#387: How To Start Tracking Your Own Biomarkers & Which Ones To Track | Become the CEO of Your Health With Dr. Darshan Shah

Today, I’m joined by the inspiring Dr. Darshan Shah, a board-certified surgeon who made the bold leap from the operating room to the forefront of longevity and functional medicine. In our conversation, Dr. Shah opens up about his own journey through burnout, chronic illness, and autoimmune disease, and shares how simple, consistent lifestyle changes became the real medicine that transformed his health. His experience revealed firsthand just how powerful habits like movement, proper nutrition, and sleep can be—often succeeding where surgery and prescriptions fell short.

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#386: How To Boost VO2 Max And HRV: The Missing Tool For Your Performance And Recovery With Rowena Gates

Today, I’m joined by the inspiring Rowena Gates, co-founder of ENG3 and the innovative mind behind the NanoVi device—a technology specialized in supporting cellular repair and resilience. Rowena Gates shares her unique journey from teaching high school and academic consulting to pioneering advanced biotech for health optimization. Her story is a powerful reminder of how unlikely paths can lead to groundbreaking innovation in longevity science.

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#385: How To Outsmart Cold & Flu Season — NAT’S Survival GUIDE For You & The Family (Supplements, Sleep, What to Avoid)

Today, let’s talk about immune support. With the festive season and colder months upon us, it’s the perfect time to focus on practical strategies to help you build a resilient, balanced immune system. I share not only the science-backed basics—like sleep, stress management, and the realities of sugar and alcohol—but also my favorite low-tech tools and innovative supplements for fortifying your body’s natural defenses. In this episode, I break down common myths about immune “boosting,” explore why balance and nuance matter, and reveal how lifestyle factors can either sabotage or supercharge your immunity.

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#384: Trading Ego For EMBODIMENT: Unlocking Deep Healing with Psilocybin & Ayahuasca | From Startup Hustle to Spiritual Awakening (with Austin Mao)

Today, I’m joined by Austin Mao, a serial entrepreneur whose personal journey with plant medicine led him from the high-pressure, Instagram-perfect startup world to founding Ceremonia—one of the leading psychedelic organizations in the U.S. In this candid conversation, Austin shares how a transformative psilocybin ceremony unraveled the layers of ego, revealing new depths of presence, embodiment, and emotional healing.

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#383: Freeze Time—Literally: Bank Your Hair Follicles For Future Skin Renewal, Hair Regrowth, and Even Wound Healing With Drew Taylor

Today, I’m joined by Dr. Drew Taylor, a trailblazer in regenerative medicine and the innovative force behind Acorn Biolabs. Dr. Taylor’s path is anything but ordinary—he went from pitching in professional baseball to pioneering non-invasive ways to collect and preserve the body’s most potent cells, all sourced from our hair follicles. His journey is a testament to the power of curiosity, resilience, and the drive to use cutting-edge science for better health and longevity.

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#382: Building Stronger Women from their 20s to their 70s: Hormones, Iron Testing, and Menopause Breakthroughs With Dr. Amy Killen

Today, I’m thrilled to welcome Dr. Amy Killen, a visionary in hormone optimization and regenerative medicine who is transforming the conversation around women’s health and longevity. In this episode, Dr. Killen shares her personal journey—from witnessing her mother’s struggle after a hip fracture, to becoming a steadfast advocate for correcting the myths and misinformation that still surround estrogen, progesterone, and testosterone optimization.

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#381: Better Than Lasers: NAD+, Spermidine, and Methylene Blue for Youthful Skin | Amitay Eshel and Anastasia Khodzhaeva

Today, I’m joined by Amitay Eshel and Anastasia Khodzhaeva, the pioneering duo behind Young Goose and two of the earliest voices to bring longevity science into the world of skincare. Amitay comes from the red light therapy space, while Anastasia’s background is rooted in cancer research and regenerative medicine—together, their bold thesis is that youthful skin is not just about appearance, it’s an energy state.

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#380: Detecting Potential Cancer With TEARS: The Surprising Future of Early Screening With Omid Moghadam

Today, I’m joined by Omid Moghadam, a serial inventor and biotech entrepreneur whose fascination with innovation has led him from the world of imaging and semiconductors to groundbreaking advancements in cancer screening. Omid shares how personal experiences—including his mother’s battle with cancer and his own early diagnosis—sparked his relentless drive to build better tools for early cancer detection.

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#379: The NEW Biohacking Stack For Gut Healing and Lifelong Vitality | Kiran Krishnan & Forrest Smith

Today, I’m sitting down with two true pioneers in the health optimization space: microbiologist Kiran Krishnan from Just Thrive, and Forrest Smith, founder of Kineon. In this episode, we bridge two often separate worlds—gut health and photobiomodulation—to explore what happens when you combine spore-based probiotics with red and near-infrared light therapy. You'll hear about the unexpected links between the gut and brain, the pivotal role of leaky gut in everything from neurodegeneration to hormone imbalance, and why Forrest started experimenting with shining red light directly on his abdomen.

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#378: Zombie Cells: The SECRET to Slowing Aging Revealed | Peptides, Senolytics, & Longevity Hacks (Halloween Edition!) With Nat Niddam

Today, I’m diving solo into a topic that’s both fascinating and a little bit spooky—senescent cells, also known as “zombie cells.” Understanding zombie cells is a crucial piece of the puzzle if you want to feel younger, stronger, and more resilient as you age. In this episode, I unpack what senescent cells are, why they’re not just harmless bystanders, and how their buildup can accelerate the aging process and drive chronic inflammation—one of the hallmarks of aging. I break down the lifestyle habits that might be quietly increasing your zombie cell load, the early warning signs your body could be giving you, and most importantly, the evidence-backed interventions you can start using right now—from exercise and diet, to cutting-edge supplements, peptides, and more.

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#377: From Leukemia SURVIVOR to Longevity Doctor: Dr. Lisa Koche on Quantum Biology, Overhyped Biohacks & True Personalization

Today, I’m joined by the remarkable Dr. Lisa Koche, a leukemia survivor turned clinician who has spent her career bridging the worlds of conventional, functional, and quantum medicine. In our conversation, Dr. Koche opens up about her unique journey—from facing a life-altering cancer diagnosis at just fifteen, to questioning conventional medical dogma, to becoming a pioneer in mitochondrial health, personalized medicine, and nervous system regulation.

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#376: Survival Tips for Perimenopause, NEW At-Home Hormone Testing & Bioidentical Myths With Dr. Carrie Jones

Today, I’m joined by the phenomenal Dr. Carrie Jones, a true powerhouse in hormone health education, to map out a sane and actionable plan for thriving through perimenopause and menopause. In our conversation, Dr. Jones breaks down what to test (and when), how to decode the difference between early and late perimenopause, and why supporting estrogen metabolism can make all the difference. She brings not only deep knowledge but also her trademark wit, making even the most complex topics feel approachable.

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