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For years, we've been told to prioritize our muscles, our hormones, and our heart health—but what about our brains? Today's conversation explores why women are at a greater risk for Dementia and Alzheimer's, why brain changes begin decades before symptoms appear, and why so many warning signs are dismissed as "just stress" or "just menopause."
Read MoreMy guest today is James LaValle R.Ph., C.C.N. M.T. DHM, DHPh, one of the pioneers in functional and metabolic medicine, and we're unpacking the silent process he calls metaflammation—the chronic, low-grade inflammation that can quietly drive everything from fatigue and insulin resistance to hormone imbalances and accelerated aging.
Read MoreFollow my NEW Instagram @longevitywithnat
Most people think that if they can just find the right mold test, they'll finally have their answer. But what if that's exactly what's keeping them stuck? In this episode, I'm joined once again by mold investigator and building health expert Jason Earle, and we challenge some of the biggest assumptions surrounding mold illness.
Read MoreFor years we've talked about longevity as if the answer is hiding in the next supplement, biomarker, or miracle molecule. But what if we've been looking at aging through far too narrow a lens? Today's guest, Dr. Marios Kyriazis, has spent decades challenging that idea by exploring aging through medicine, complexity science, cybernetics, and even philosophy.
Read MoreIf you've been hearing everyone talk about exosomes but still aren't exactly sure what they are—or whether they're actually worth the hype—this episode is for you. Today I'm joined once again by Amitay Eshel and Anastasia Khodzhaeva from Young Goose to separate the science from the marketing and unpack what exosomes are really doing inside your skin.
Read MoreToday, I’m joined by the insightful Dr. Scott Sherr, a pioneer in health optimization and mitochondrial medicine. In our conversation, Dr. Sherr introduces his groundbreaking concept—the "sympathetic spiral of doom"—and explains why so many high performers end up burned out, frustrated, and feeling like their nervous systems are working against them.
Read MoreToday, I’m joined by Dr. Teo Soleymani, a renowned dermatological oncologist whose unique vantage point bridges the worlds of conventional medicine and longevity science. As someone who sees the real consequences of UV damage in his surgical practice while also advocating for a balanced, evidence-driven approach to sunlight and skin health, Dr. Teo Soleymani isn’t afraid to challenge the most entrenched ideas in modern skincare.
Read MoreToday, I’m joined by Alex Kikel—a name that’s become synonymous with pushing the frontiers of biology, performance, and healing. Alex is the kind of person who, when told “there’s nothing more we can do,” responds with, “but what if that’s not true?” In our conversation, he shares the pivotal moments that made him question everything about the standard approach to health, including his personal story of reversing serious conditions when traditional solutions failed.
Read MoreToday, I’m joined once again by the innovative Ian Mitchell, a name familiar to anyone passionate about radical longevity, biohacking, and pushing the boundaries of human performance. In this conversation, Ian pulls back the curtain on the science and surprising applications of C60—known as the “buckyball” molecule—and why it’s become such a powerful tool for both peak performance and healthy aging.
Read MoreToday, I’m joined by Nicole Bell, an accomplished engineer who made an unexpected leap from designing cutting-edge surgical robotics to becoming a powerful advocate for better diagnostics in tick-borne diseases. Nicole’s story is both deeply personal and urgent: after her husband was misdiagnosed with early-onset Alzheimer’s—only to later discover the true culprit was hidden tick-borne infections—she set out to uncover why our medical system misses these subtle yet devastating conditions.
Read MoreToday, I’m sitting down with the trailblazing Dr. Tyna Moore, a pioneer in reframing the conversation around GLP-1 medications. Instead of focusing solely on weight loss, Dr. Moore reveals how these powerful molecules can open a critical window to reset our health story—if we’re willing to harness that opportunity wisely.
Read MoreToday, I’m joined by Zach Abbott, a biotech innovator who took an unconventional path—from pharmaceutical science to the front lines of consumer health. Instead of following the well-worn route of drug development, Zach set his sights on bringing cutting-edge biotechnology directly to people, creating products designed not just for convenience, but for genuinely transforming our relationship with microbiology.
Read MoreToday, I’m joined by Dr. Robin Rose, a double board-certified gastroenterologist and internal medicine physician who has become a true pioneer in the space of functional and precision medicine. Driven by a relentless curiosity that survived even the most rigid medical training, Dr. Rose shares how her quest to answer “why” led her beyond conventional medicine into root-cause healing, patient-centered care, and the world of gut health, biochemistry, and the microbiome.
Read MoreToday, I’m joined by Dr. Andrew Salzman, a pioneer in NAD research whose work has spanned everything from pediatric sepsis to cutting-edge longevity science. Dr. Salzman dives deep into why NAD isn’t just another supplement buzzword, but a central molecule powering our energy, resilience, and even fertility.
Read MoreToday, I’m joined by the inspiring Dr. Anshul Gupta, a conventionally trained family physician who completely reimagined thyroid care after his own life and health hit a breaking point. Dr. Gupta shares how his battle with fatigue, weight gain, and relentless gut pain led him down a path beyond prescriptions, ultimately transforming his personal health and medical practice. Through functional medicine, he found a way out of his own struggle—and uncovered what so many thyroid patients are missing.
Read MoreToday, I’m joined by the incredibly insightful Donna Jackson Nakazawa, a science journalist and bestselling author whose work bridges the worlds of neuroscience, storytelling, and personal transformation. Donna has a unique gift for translating complex brain science into real-life strategies—and she’s not afraid to weave in her own powerful journey, from childhood trauma and autoimmune challenges to her fierce quest for hope and healing.
Read MoreToday, I’m joined by Dr. William Davis, a cardiologist-turned-gut detective and bestselling author behind Wheat Belly, Super Gut, and Super Body. In this episode, Dr. Davis breaks down what it really means to have youthful, functional muscle, why maintaining the muscle of your 20s and 30s is about so much more than hitting the gym, and how missing microbes—like L. reuteri—might be the secret to restoring your strength and energy.
Read MoreToday, I’m joined by Kyal Van Der Leest, an innovative naturopath, nutritionist, and founder of LVLUP Health, whose formulas are changing the way we think about effective supplementation. Kyal’s journey is deeply personal: from caring for his mother through a long battle with cancer, to overcoming his own intense health struggles with mold illness. These experiences led him to push past superficial fixes and dig deep into what really works for healing and optimizing the body.
Read MoreToday, I'm joined by Dr. Taz Bhatia, a trailblazing integrative medicine physician, entrepreneur, and leading voice in women's health and longevity. In our conversation, Dr. Taz opens up about how her personal health challenges as a conventionally-trained MD led her to explore nutrition, Chinese medicine, and Ayurveda, inspiring her to reimagine what it means to truly care for the whole person.
Read MoreToday, I’m flying solo to tackle a topic that’s essential for anyone invested in their health: how to truly vet your supplements. With new products hitting the shelves daily and wellness marketing louder than ever, it’s easy to get swept up in the latest hype—but more isn’t always better, and sometimes it can actually make things worse. In this episode, I break down the six key filters I use before adding any supplement to my routine, from understanding your baseline biomarkers to decoding red flags in marketing language like “studies show.” I dig into common pitfalls—like why “natural” doesn’t automatically mean safe, the real risks of fat-soluble vitamin toxicity, and how to spot quality with third-party certifications.
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