Podcast — NAT NIDDAM

Covering the latest research directly from the experts across peptides, epigenetics, actionable biohacking, data-driven healthtech & more.

#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny

#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny

Today, I'm joined by the inspiring Leslie Kenny, Oxford-based longevity expert and a living example of turning adversity into vitality. After being told at 39 that she had lupus, rheumatoid arthritis, and just five years to live, Leslie defiantly forged a new path—reversing her diagnoses, restoring her thyroid health, and even welcoming a healthy baby girl at 43. Her story is a testament to the power of questioning the status quo, honoring the wisdom within our bodies, and refusing to accept decline as inevitable.

#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana

#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana

Today, I’m joined by the extraordinary Dr. Natalie Yivgi-Ohana, a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind—Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age.

#418: The Science of NAD+: Why Precursors & IVs Fail Without This Step With Courtney Van Bussum

#418: The Science of NAD+: Why Precursors & IVs Fail Without This Step With Courtney Van Bussum

Today, I’m joined by the insightful Courtney Van Bussum, a biomedical engineer and entrepreneur who has become a rising force in longevity science. Courtney shares how growing up in a family of healthcare innovators shaped her journey, and how she pivoted from startup life to tackling age-related challenges—especially when COVID brought her back to her roots and reignited her passion for cellular health.

#417: Depression and Weight Gain In Kids & Adults | A Long Term Post-COVID Problem & How To Reverse It With Dr. Cynthia Keller

#417: Depression and Weight Gain In Kids & Adults | A Long Term Post-COVID Problem & How To Reverse It With Dr. Cynthia Keller

Today, I’m joined by the innovative Dr. Cynthia Keller, a pediatrician whose passion for integrative and functional medicine has reshaped how we understand post-COVID health challenges. Dr. Keller opens up about her journey from conventional medicine to designing unique solutions for children and families, revealing how her care, presence, and determination to “solve the unsolvable” led to breakthroughs in treating mood changes, weight gain, and energy loss after COVID.

#416: The Cardiovascular Crisis No One Talks About: Women, Midlife & Nitric Oxide Explained With Cathy Eason

#416: The Cardiovascular Crisis No One Talks About: Women, Midlife & Nitric Oxide Explained With Cathy Eason

Today, I’m joined by the remarkable Cathy Eason, whose work in the nitric oxide and vascular health space is changing the conversation around resilience and heart health for midlife women. Cathy dives into why cardiovascular disease is still the number one threat to women globally, and how the drop in estrogen during menopause impacts nitric oxide production—an overlooked factor that quietly influences everything from energy to cognition.

#415: The Untold Truth About Heart Health: (Women, Genetics & the JOY of Longevity) | Dr. Regina Druz Reveals All

#415: The Untold Truth About Heart Health: (Women, Genetics & the JOY of Longevity) | Dr. Regina Druz Reveals All

Today, I’m joined by Erin Ryan, my producer and long-time collaborator, for a special Q&A episode powered entirely by your questions. After our bioregulator deep dive with Dr. Bill Lawrence, the response was overwhelming—so many of you reached out with insightful queries about bioregulators, peptides, and the nuances between natural and synthetic options. Erin and I decided to tackle the most common themes, unpacking everything from organ versus system signaling to how bioregulators actually survive digestion.

#414: The Untold Truth About Heart Health: (Women, Genetics & the JOY of Longevity) | Dr. Regina Druz Reveals All

#414: The Untold Truth About Heart Health: (Women, Genetics & the JOY of Longevity) | Dr. Regina Druz Reveals All

Today, I’m joined by the trailblazing Dr. Regina Druz, a cardiologist who reimagined heart health after years in elite academic medicine. In this episode, Dr. Druz opens up about her journey from the traditional halls of Cornell and New York Presbyterian to creating truly personalized, preventive, and holistic programs for her patients—even when it meant leaving behind the medical mainstream.

#413: Mold, Toxins, and the Cell Danger Response: How to Reclaim Energy and Resilience With Dr. Clement Lee, NMD

#413: Mold, Toxins, and the Cell Danger Response: How to Reclaim Energy and Resilience With Dr. Clement Lee, NMD

Today, I’m joined by the thoughtful Dr. Clement Lee, a naturopathic doctor blending ancient wisdom from Chinese medicine with cutting-edge regenerative therapies. In this episode, Dr. Lee gets real about why people can feel deeply unwell long before anything shows up on standard labs—and how subtle issues like limbic system stress, toxins, and chronic inflammation quietly undermine our vitality.

#412: From Anti-Aging to Age Reversal: The Exosome & Copper Peptide Breakthrough For Younger Skin With Debbi Barber and Dr. Jordan Plews

#412: From Anti-Aging to Age Reversal: The Exosome & Copper Peptide Breakthrough For Younger Skin With Debbi Barber and Dr. Jordan Plews

Today, I’ve got a conversation that goes deep into the cutting edge of regenerative skin health with two exceptional guests: Debbi Barber, founder and muse of Vitali Skincare, and Dr. Jordan Plews, a biochemical engineer and stem cell researcher. We discuss the science and practical realities of exosomes, stem cells, and copper peptides—breaking down not just what makes skin look younger, but what truly keeps it biologically healthier and more resilient as we age.

#411: Rethinking Heart Health: Surrender, Sunlight, and Structured Water With Dr. Stephen Hussey

#411: Rethinking Heart Health: Surrender, Sunlight, and Structured Water With Dr. Stephen Hussey

Today, I’m joined by Dr. Stephen Hussey—a clinician, author of Understanding The Heart, and a powerful force in rethinking everything we thought we knew about heart disease. Dr. Hussey’s own journey began with type 1 diabetes as a child, and despite living a healthy, active lifestyle, he experienced a widowmaker heart attack at just 34 years old. In our conversation, he opens up about what it was like to face this crisis with “perfect” lab numbers, how it challenged his entire perspective, and ultimately led him to a radical new understanding of heart health and longevity.

#:410 Reversing Burnout: Turmeric, Gut Health, and Circadian Rhythms Explained With Shivani Gupta

#:410 Reversing Burnout: Turmeric, Gut Health, and Circadian Rhythms Explained With Shivani Gupta

Today, I’m joined by the wonderful Dr. Shivani Gupta, a true force in bridging ancient Ayurvedic wisdom with cutting-edge modern research on inflammation and healthy aging. She recently authored The Inflammation Code. Dr. Shivani opens up about her deeply personal motivation—from witnessing her grandfather’s preventable health decline to spending years in both traditional and scientific studies, ultimately earning a PhD focused on turmeric and chronic inflammation.

#409: How to LIVE YOUNG for a Lifetime: The Real Secrets of Mindset, Medicine & Longevity | Personalized Health Explained With Dr. Jeffrey Gladden

#409: How to LIVE YOUNG for a Lifetime: The Real Secrets of Mindset, Medicine & Longevity | Personalized Health Explained With Dr. Jeffrey Gladden

Today, I’m joined by the inspiring Dr. Jeffrey Gladden—a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept “normal for your age” as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same.

#408: The Surprising Truth About Metabolomics, Stress, and Slowing Aging (Peptides, Heavy Metals & Foundational Health Secrets) With Gus Vickery

#408: The Surprising Truth About Metabolomics, Stress, and Slowing Aging (Peptides, Heavy Metals & Foundational Health Secrets) With Gus Vickery

Today, I’m sitting down with Dr. Gus Vickery, a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine.

#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why “Healthy Sedentary” Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon

#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why “Healthy Sedentary” Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon

Today, I’m joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a “healthy sedentary person” and reveals the major role of intramuscular fat in metabolic dysfunction.

#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

Today, I’m joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.

#405: Heart Attacks Aren’t What You Think | The Plaque LIE That Changes Everything (Cardiology 2.0) With Dr. Sanjay Bhojraj

#405: Heart Attacks Aren’t What You Think | The Plaque LIE That Changes Everything (Cardiology 2.0) With Dr. Sanjay Bhojraj

Today, I’m joined by the deeply thoughtful and refreshingly honest Dr. Sanjay Bhojraj, a self-described “curious cardiologist” who spent decades treating heart attacks in the cath lab — before stepping away to ask a bigger question: Why are we waiting for the crisis instead of preventing it?

#404: The Dirty Truth About Your Home’s WATER (And Why Most Filters Including Reverse Osmosis Don’t Cut It) With Charles Bohdy and Victor Sagalovsky

#404: The Dirty Truth About Your Home’s WATER (And Why Most Filters Including Reverse Osmosis Don’t Cut It) With Charles Bohdy and Victor Sagalovsky

Today, I’m joined by Charles Bohdy, a true innovator in water purification technology, and Victor Sagalovsky, a passionate advocate for bringing the science of water quality into our daily lives. Together, we take a deep dive into the unseen world of the water running through our homes—exploring not just its purity, but its hidden potential to support our biology in ways most of us have never considered.

#403: What’s REALLY In Your Food? | Dark Secrets of Ultra-Pasteurized Milk, Natural Flavors & Microplastics EXPOSED With Ben Katz

#403: What’s REALLY In Your Food? | Dark Secrets of Ultra-Pasteurized Milk, Natural Flavors & Microplastics EXPOSED With Ben Katz

Today, I’m joined by Ben Katz—better known online as Mr. Mass Spec —an academic analytical chemist from UC Irvine whose mission is to uncover what’s really in our everyday foods, drinks, and products. Ben reverse engineers everything from Taco Bell meat to Doritos, and sometimes even entire industries, using cutting-edge mass spectrometry. His curiosity and expertise have made him a go-to source for those wanting to know what’s hiding behind vague ingredient labels and “natural flavors.”

#402: Gut Reset: The SECRET Signals for Longevity Revealed | How to Heal Your Microbiome, Banish Bloating, and Build Resilience With Nat Niddam

#402: Gut Reset: The SECRET Signals for Longevity Revealed | How to Heal Your Microbiome, Banish Bloating, and Build Resilience With Nat Niddam

Today, I’m kicking off the new year with a back-to-basics deep dive into one of the most pivotal yet overlooked foundations of longevity: gut health. Over the past episodes, we’ve explored everything from gene therapy to advanced tech, but it all comes back to the habits and systems we rely on every single day—and the gut is right at the center of that equation.

#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff

#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff

Today, I’m joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal “aha” moments that led her to champion true weight health, not just weight loss.