Posts tagged methylation
#464: Brain POWER: The Creatine Revolution, Exercise Snacks, and the Age of Energy | Dan Pardi
#464: Brain POWER: The Creatine Revolution, Exercise Snacks, and the Age of Energy | Dan Pardi

Today, I’m joined by Dan Pardi, a pioneering researcher who has dedicated years to understanding sleep, performance, and—the real focus of today’s conversation—the science of human energy. Dan unpacks how modern life is quietly draining our brain’s battery, and why brain energy, not just the march of time, could be the hidden driver of longevity.

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Exercise & Fitness, Brain Health, Women’s HealthLorenz Ralph Gañolongevity, brain energy, creatine, sleep performance, exercise snacks, cognitive performance, chronic stress, screen time, blood flow, default mode system, neurodegenerative diseases, adenosine, ATP, mitochondrial health, perimenopause, menopause, muscle mass, muscle quality, functional muscle, magnesium, methylation, women’s health, hormone fluctuations, perimenopause supplements, sleep deprivation, personalized nutrition, bioregulators, ancestral health, energy metabolism, brain fog, cognitive decline, Dan Pardi
#418: The Science of NAD+: Why Precursors & IVs Fail Without This Step With Courtney Van Bussum
#418: The Science of NAD+: Why Precursors & IVs Fail Without This Step With Courtney Van Bussum

Today, I’m joined by the insightful Courtney Van Bussum, a biomedical engineer and entrepreneur who has become a rising force in longevity science. Courtney shares how growing up in a family of healthcare innovators shaped her journey, and how she pivoted from startup life to tackling age-related challenges—especially when COVID brought her back to her roots and reignited her passion for cellular health.

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Cellular Health, Metabolic HealthLorenz Ralph GañoKeywords: NAD+, NADH, salvage pathway, CD38 enzyme, NNMT enzyme, 1-MNA, methylation, mitochondrial health, cellular energy, inflammation, longevity, aging, precursors (NR, NMN), NAD+ infusions, subcutaneous NAD+, transdermal NAD, creatine, Qualia Creatine Plus, liver detox, Complete Liver Complex, microvasculature, nitric oxide, metabolic health, homocysteine, sirtuins, PARPs, redox balance, circadian rhythm, exercise, ketones
#417: Depression and Weight Gain In Kids & Adults | A Long Term Post-COVID Problem & How To Reverse It With Dr. Cynthia Keller
#417: Depression and Weight Gain In Kids & Adults | A Long Term Post-COVID Problem & How To Reverse It With Dr. Cynthia Keller

Today, I’m joined by the innovative Dr. Cynthia Keller, a pediatrician whose passion for integrative and functional medicine has reshaped how we understand post-COVID health challenges. Dr. Keller opens up about her journey from conventional medicine to designing unique solutions for children and families, revealing how her care, presence, and determination to “solve the unsolvable” led to breakthroughs in treating mood changes, weight gain, and energy loss after COVID.

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Longevity & Biohacking, Gut Health & MicrobiomeLorenz Ralph Gañopost-COVID symptoms, nutrient depletion, neurotransmitters, tryptophan, serotonin, dopamine, mood changes, metabolism, recovery, peptides, bioregulators, integrative medicine, pediatric care, GI pain, functional medicine, sleep problems, Oslo Sleepbuds, NAD+ precursors, neuroinflammation, microbiome, methylation, zinc deficiency, B6 (P5P), methylfolate, weight gain, sugar cravings, catecholamines, antidiuretic hormone, mast cell issues, glyphosate, infant gut health, autoimmune disease