Posts tagged mitochondrial function
#469: Electrolytes, Completely REINVENTED: The New Science of Hydration + Why Magnesium Matters More Than You Think With Wade LightHeart

Today, I’m joined by Wade Lightheart, a true thought leader in the world of biohacking and co-founder of BiOptimizers. Wade has spent decades diving deep into the science of longevity—questioning what really moves the needle for our long-term health, and challenging some of the biggest assumptions in the wellness industry.

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#467: The (Misunderstood) Plant Compound That’s Turning Back the Clock | With Nat Niddam

Today, I’m diving solo into a topic that’s truly at the heart of everything I do: longevity—specifically, how to actually feel vibrant and strong as we age, not just rack up more years on the calendar. I break down the science behind aging, the real reasons why our repair systems start to slow down, and the practical ways we can take charge, starting right now.

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#461:Why Only 8 Proven Interventions Work | Extend LIFE & Healthspan With Science Not Hype With Dr. Bill Lawrence

Today, I’m joined by Dr. Bill Lawrence, a leading researcher in longevity and pioneer in clinical studies on peptide bioregulators. Over the past eight years, Dr. Lawrence has dedicated himself to asking the big questions in longevity science: Do these interventions really work, and which strategies actually move the needle when it comes to living longer, healthier lives?

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#454: From Burnout to Balance: Rebuilding Cellular Energy & Getting Out Of Fight Or Flight With Scott Sherr

Today, I’m joined by the insightful Dr. Scott Sherr, a pioneer in health optimization and mitochondrial medicine. In our conversation, Dr. Sherr introduces his groundbreaking concept—the "sympathetic spiral of doom"—and explains why so many high performers end up burned out, frustrated, and feeling like their nervous systems are working against them.

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#439: Reclaiming Metabolism: The SECRET Molecule Transforming Women's Health (Belly Fat, Brain Power & Beyond) With Siobhan Mitchell PhD

Today, I’m joined by the insightful Siobhan Mitchell PhD, a leading expert on women’s health, mitochondria, and metabolic resilience. In our conversation, Siobhan reveals why so many women in their 30s and 40s feel like their metabolism is suddenly “broken,” and unpacks the real science behind what’s happening beneath the surface—especially as our hormones begin to shift.

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#437: Unmasking Thyroid Dysfunction: How Optimizing Your Thyroid Transforms Longevity, Mood, and Metabolism With Dr. Amie Hornaman

Today, I’m joined by the incredible Dr. Amie Hornaman, a leading thyroid expert and author of the brand new book, The Thyroid Fix. In our conversation, Dr. Hornaman opens up about her personal struggle with undiagnosed thyroid disease—a journey marked by frustrating medical gaslighting and the dismissive “you’re normal” diagnoses from doctor after doctor. She reveals how that experience led her to become a passionate advocate for women (and men) suffering from thyroid dysfunction and a pioneer in holistic, root-cause approaches to healing.

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#428: Poop, Peptides & The Power of Microbiome | The Secret Longevity Organ With Dr. Grace Liu

Today, I'm joined by Dr. Grace Liu, often known as the “Gut Goddess,” a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right—Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself.

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#424: Part 2 - Follow Up To Dr. Bill Lawrence Episode: Answering More Of Your Bioregulator Questions With Nat Niddam & Erin Ryan

Today, I’m joined by Erin Ryan, my producer, for a special follow-up episode where we tackle your most pressing questions about bioregulators and peptides. After our wildly popular Bill Lawrence interview, the Longevity Podcast community sent in a wave of thoughtful queries—from cancer concerns to menopause, sourcing, and practical tips.

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#413: Mold, Toxins, and the Cell Danger Response: How to Reclaim Energy and Resilience With Dr. Clement Lee, NMD

Today, I’m joined by the thoughtful Dr. Clement Lee, a naturopathic doctor blending ancient wisdom from Chinese medicine with cutting-edge regenerative therapies. In this episode, Dr. Lee gets real about why people can feel deeply unwell long before anything shows up on standard labs—and how subtle issues like limbic system stress, toxins, and chronic inflammation quietly undermine our vitality.

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#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why “Healthy Sedentary” Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon

Today, I’m joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a “healthy sedentary person” and reveals the major role of intramuscular fat in metabolic dysfunction.

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#382: Building Stronger Women from their 20s to their 70s: Hormones, Iron Testing, and Menopause Breakthroughs With Dr. Amy Killen

Today, I’m thrilled to welcome Dr. Amy Killen, a visionary in hormone optimization and regenerative medicine who is transforming the conversation around women’s health and longevity. In this episode, Dr. Killen shares her personal journey—from witnessing her mother’s struggle after a hip fracture, to becoming a steadfast advocate for correcting the myths and misinformation that still surround estrogen, progesterone, and testosterone optimization.

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