#449: I Never Said That! - Dr. Tyna Moore on How Her GLP-1 Microdosing Message Was Misunderstood and What She Actually Recommends
Today, I’m sitting down with the trailblazing Dr. Tyna Moore, a pioneer in reframing the conversation around GLP-1 medications. Instead of focusing solely on weight loss, Dr. Moore reveals how these powerful molecules can open a critical window to reset our health story—if we’re willing to harness that opportunity wisely.
In this episode, we dive into everything from inflammation, metabolism, and autoimmune issues to the non-negotiable importance of strength training for true longevity. Dr. Moore shares her early insights into microdosing GLP-1s, why muscle mass matters far more than the number on the scale, and the surprising way these drugs can shine a light on underlying metabolic dysfunction.
If you’re curious about using cutting-edge medicine alongside foundational lifestyle changes, this conversation is packed with practical wisdom, a bit of tough love, and a whole lot of inspiration to help you rewrite your health journey for the better.
Learn more from Dr. Tyna Moore below:
Website: https://www.drtyna.com/
Podcast: https://podcasts.apple.com/us/podcast/the-dr-tyna-show/id1577258582
Instagram: https://www.instagram.com/drtyna
YouTube: https://www.youtube.com/@drtyna
Substack: https://drtyna.substack.com/
What We Discuss:
Welcome, host introduction, and overview ... 00:00:00
Stigma, marketing, and confusion around GLP-1 use ... 00:05:38
True microdosing vs. standard dosing explained ... 00:08:18
Strength training as essential during GLP-1 therapy ... 00:12:06
GLP-1 medications as windows of opportunity for health resets ... 00:13:24
Risks of extreme thinness and frailty for longevity ... 00:15:11
Why metabolic health matters at every age ... 00:20:56
PCOS renamed as a metabolic disease ... 00:26:07
Senescence, exercise, and aging ... 00:28:10
Dr. Tyna Moore’s GLP-1 research and patient findings ... 00:30:34
GLP-1s reveal deeper metabolic issues ... 00:37:28
Differentiating semaglutide, tirzepatide, retatrutide ... 00:39:41
Liver fat, lean mass loss, and weight regain challenges ... 00:43:59
Personalized dosing, side effects, and patient variability ... 00:46:53
Digestive health, SIBO, and supporting GLP-1 users ... 00:52:37
Lab monitoring and practical implementation ... 01:01:04
Immune impacts, senescence, and metabolic improvements ... 01:02:29
Lifestyle first: exercise, peptide stacking, and fundamentals ... 01:10:49
Cautious optimism for the future of GLP-1s ... 01:12:08
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For Transparency:
Some episodes of the Longevity With Nathalie Niddam podcast are supported by partners whose products or services may be discussed during the show. The host may receive compensation or earn a minor commission if you purchase through affiliate links at no extra cost to you. All opinions shared are those of the host and guests, based on personal experience and research, and do not necessarily represent the views of any sponsor. Sponsorships do not imply medical endorsement or approval by any healthcare provider featured on this podcast.