Posts in Longevity
#442: The High-Performance Guide to Supplements With Kyal Van Der Leest

Today, I’m joined by Kyal Van Der Leest, an innovative naturopath, nutritionist, and founder of LVLUP Health, whose formulas are changing the way we think about effective supplementation. Kyal’s journey is deeply personal: from caring for his mother through a long battle with cancer, to overcoming his own intense health struggles with mold illness. These experiences led him to push past superficial fixes and dig deep into what really works for healing and optimizing the body.

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#440: The Ultimate Supplement Checklist BEFORE You Buy: Safety, Quality, and Evidence-Based Picks | SOLO With Nat Niddam

Today, I’m flying solo to tackle a topic that’s essential for anyone invested in their health: how to truly vet your supplements. With new products hitting the shelves daily and wellness marketing louder than ever, it’s easy to get swept up in the latest hype—but more isn’t always better, and sometimes it can actually make things worse. In this episode, I break down the six key filters I use before adding any supplement to my routine, from understanding your baseline biomarkers to decoding red flags in marketing language like “studies show.” I dig into common pitfalls—like why “natural” doesn’t automatically mean safe, the real risks of fat-soluble vitamin toxicity, and how to spot quality with third-party certifications.

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#436: Is Your Body’s Terrain Hospitable For Cancer? Affordable Lab Tests, Metabolic Flexibility, and Emotional Foundations With Dr. Nasha Winters

Today, I’m thrilled to welcome Dr. Nasha Winters back to the show for part two of our powerful conversation. As a trailblazer in integrative oncology and a passionate advocate for the “metabolic terrain” approach to health, Dr. Winters brings both deep expertise and a truly holistic perspective to the complex world of cancer and longevity. In this episode, she doesn’t just share concepts—she takes us into the heart of what it means to test, assess, and address our own health in real life, especially when we’re facing major diagnoses and difficult decisions.

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#434: Are You Aging Like Someone Else? (How To Find Your PERSONAL Path to Healthspan) With Sandra Kaufmann.

Today, I’m joined by the one and only Dr. Sandra Kaufmann—a true pioneer in the field of personalized longevity medicine and the creative force behind the Kaufman Protocol. In this episode, Sandra shares how a personal curiosity about why we age at the cellular level ultimately drew her away from a successful anesthesia career and into the world of building longevity strategies for real people. She opens up about the moment longevity became more than just an intellectual pursuit, and the surprising ways her work has grown into a global movement.

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#431: Humic and Fulvic Minerals: Nature’s Solution for Energy, Detox, and Lasting Health With Caroline Alan

Today, I’m joined by the insightful Caroline Alan, author of The Mineral Reset and co-founder of Beam Minerals. Caroline Alan shares her powerful story—a decade-long journey from chronic fatigue, brain fog, adrenal burnout, and persistent health challenges to discovering the true foundation of her recovery: replenishing trace minerals. After years of searching for answers and seeing countless specialists, it wasn’t another diet or protocol that brought her back to health, but addressing a deep, often-overlooked mineral deficiency.

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#430: Most Impactful Pod Moments This Year: Mitochondrial Transplants, Weight Loss, Resilience Through Trauma, Heart Tests & Tryptophan After COVID

Today, I’m pulling together some of the most impactful conversations from the last three months on the Podcast. From breaking down the pitfalls of trendy weight loss drugs to uncovering silent heart health risks, and exploring how mitochondrial transplants and trauma healing are rewriting the story of resilience, these moments have truly shifted my perspective on what it means to pursue lasting wellness.


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#428: Poop, Peptides & The Power of Microbiome | The Secret Longevity Organ With Dr. Grace Liu

Today, I'm joined by Dr. Grace Liu, often known as the “Gut Goddess,” a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right—Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself.

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#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

Today, I’m joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.

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#388: Nat’s Ultimate Gift Guide for Longevity Fans: Biohacks, Wellness Gadgets, and Black Friday Deals

Today, I’m sharing my go-to biohacking strategies and supplement stacks for leveling up your health and longevity. After years of testing the latest tech and science-backed interventions, I’ve curated smart bundles for better sleep, sharper focus, and lasting energy—perfect for your own routine or thoughtful holiday gifting. Go To NatNiddam.com/giftguide for all the holiday deals!

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#379: The NEW Biohacking Stack For Gut Healing and Lifelong Vitality | Kiran Krishnan & Forrest Smith

Today, I’m sitting down with two true pioneers in the health optimization space: microbiologist Kiran Krishnan from Just Thrive, and Forrest Smith, founder of Kineon. In this episode, we bridge two often separate worlds—gut health and photobiomodulation—to explore what happens when you combine spore-based probiotics with red and near-infrared light therapy. You'll hear about the unexpected links between the gut and brain, the pivotal role of leaky gut in everything from neurodegeneration to hormone imbalance, and why Forrest started experimenting with shining red light directly on his abdomen.

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#362: Redefining Oral Health: The SURPRISING Link Between Your Mouth, Disease & Longevity (How A Spit Test Could Save Your Life) | with Dr. Nammy Patel

Discover how your mouth holds the key to your overall health in this eye-opening episode with functional dentist Dr. Nammy Patel. We explore the powerful connection between oral health and systemic diseases like Alzheimer’s, heart disease, and cancer. Learn how tongue posture, jaw development, nitric oxide production, and the oral microbiome affect your vitality, sleep, and longevity. Dr. Patel also shares actionable tips and cutting-edge diagnostics—like oral microbiome testing and spit analysis—that are transforming preventative care from the inside out.

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#360: How Liz Parrish Is REWRITING the Rules of Aging (Gene Therapy, Telomeres & The Future of Longevity)

Today, I’m joined by the trailblazing Liz Parrish, a true pioneer in the world of longevity science and regenerative medicine. Liz doesn’t just talk about cutting-edge gene therapies—she’s the first patient to actually undergo many of them herself. In our conversation, Liz shares how her journey from stem cell advocacy to biotech innovation was fueled by a deeply personal mission: her son’s diagnosis with type 1 diabetes.

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#352: Biohacker’s DREAM: How Plant Exosomes Deliver Cellular Power Like Never Before | Dr. Jeffrey Gross

Today, I’m welcoming back Dr. Jeffrey Gross, a true pioneer in the regenerative longevity space. You might remember our earlier episode where we explored the transformative science of human exosomes—but today, we’re going even further, straight into the fascinating world of plant exosomes. In our conversation, Dr. Gross reveals how rediscovering his passion for molecular biology led him to a powerful realization: plants, through their exosomes, have found a natural way to deliver high-potency nutrients right where our bodies need them most.

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#351: How to Rewire Your Gut (and Mind) For Health: Coffee, Microbiome DIVERSITY, and The Power of Belief | Dr. Vincent Pedre

I’m thrilled to bring you another fantastic episode that’s all about gut health—a topic I know so many of us care deeply about, whether you’re dealing with digestive issues yourself or just looking to optimize your vitality and longevity. Today, I’m joined by the brilliant Dr. Vincent Pedre, one of the most sought-after experts in functional medicine and an incredible advocate for what he calls “gut-centric medicine.” In our conversation, Dr. Pedre shares his inspiring journey from being a tightly-wound, needle-phobic med student to becoming a leader in gut health.

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#349: Jaw-Dropping Moments From The Last 6 Months: The Conversations Still Stuck in My Head With Nat Niddam (Solo)

Today, I've got something special for you: a solo episode where I look back at the past six months and handpick the five episodes and ideas that truly changed the game for me—and, based on your feedback, for many of you too. I'm excited to share the biggest, most paradigm-shifting insights that have transformed how I think about aging, prevention, healing, and what it really means to extend your health span. From the mind-blowing potential of exosomes in regenerative medicine, to a controversial conversation about whether mammograms are actually the best approach for breast cancer screening, to the huge role mitochondria play in vibrant health—and the power of methylene blue as a mitochondrial “supercharger,” I’m breaking down the real lessons, not just interesting trivia.

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#346: How Wearables, Biological Age Tests, And AI Are Shaping the Future Of Longevity With David Korsunsky

Today I’m joined by my friend and fellow biohacker, Dave Korsunsky, founder of Heads Up Health. In this episode, we take you on a journey through the evolution of biohacking—from the early days when continuous glucose monitors were a novelty and cryotherapy sounded like science fiction, all the way to the sophisticated, data-driven tools we have at our fingertips today. We get real about how overwhelming it can feel to track the flood of information from wearables, labs, and health gadgets—and why making sense of your personal metrics is more important than ever.

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#340: Dave Asprey on Biohacking, Longevity, and Living to 180 (Kale Is Out, Stem Cells Are In) | The Longevity Revolution Explained

I had the chance to sit down with one of the original pioneers of the biohacking movement: Dave Asprey. You probably know Dave as the founder of Bulletproof, the mastermind behind putting butter in coffee, and the creator of Upgrade Labs and the Biohacking Conference. He’s also a four-time New York Times bestselling author. In our chat, Dave and I explore the evolution of biohacking and how it’s blossomed into the multi-billion dollar industry it is today. We dig into why Dave believes energy—not just time or money—is the actual currency of longevity and high performance.

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#339: Clean Supplements and Protein Powders: What Every Health-Conscious Consumer Needs to Know With Oliver Amdrup-Chamby

I’m joined today by Oliver Amdrup-Chamby, the co-founder of Puori and a true trailblazer in supplement transparency and quality. We break down everything you need to know to become a more informed consumer, from how to avoid hidden contaminants like heavy metals, pesticides, and microplastics, to why oxidation in fish oil is such a big deal, and the real story behind protein powders—especially the plant-based ones.

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#309: Cordycepin and Methylene Blue: Two Game-Changers For Better Energy, Focus, Sleep, and So Much More With Dr. Scott Sherr

Today we’re talking about methylene blue—aka the stuff that biohackers love, and journalists love to call "fish tank cleaner." Discover how methylene blue can serve as a redox cycling agent, enhancing mitochondrial function, supporting immune health, and even boosting mood. Dr. Scott Sherr, the COO of Troscriptions and Director of Education at HOMeHOPe is here to break it all down, along with why some people (including my own father, by accident) have turned very blue using this stuff. 

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#303: The Fasting PLAYBOOK: Nathalie Niddam Reveals Top Strategies for Health & Longevity

In episode 303, Nathalie explores the fascinating and multi-faceted practice of fasting. Today’s episode uncovers the various types of fasting—from intermittent fasting and water fasting to the more intensive dry fasting and the innovative fasting mimicking diet.* Nathalie discusses the myriad benefits of fasting, such as improved metabolic health, body composition, reduced inflammation, and enhanced gut health. 

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