Posts tagged clinical trials
#467: The (Misunderstood) Plant Compound That’s Turning Back the Clock | With Nat Niddam
#467: The (Misunderstood) Plant Compound That’s Turning Back the Clock | With Nat Niddam

Today, I’m diving solo into a topic that’s truly at the heart of everything I do: longevity—specifically, how to actually feel vibrant and strong as we age, not just rack up more years on the calendar. I break down the science behind aging, the real reasons why our repair systems start to slow down, and the practical ways we can take charge, starting right now.

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Longevity & Healthy Aging, AshwagandhaLorenz Ralph GañoLongevity, aging, healthspan, stem cells, Stem Regen, epigenetics, peptides, bioregulators, mitochondrial function, autophagy, telomeres, proteostasis, inflammaging, dysbiosis, gut microbiome, sirtuins, NRF2, oxidative stress, cardiovascular health, metabolic disease, IGF-1, grip strength, six-minute walk test, Berg Balance Scale, stress resilience, ashwagandha, withanolides, cognitive health, BDNF, clinical trials
#465: Personalizing GLP-1 Medications: The Role of Genetics in Weight Loss and Side Effects With Noura Abul-Husn M.D. Ph.D
#465: Personalizing GLP-1 Medications: The Role of Genetics in Weight Loss and Side Effects With Noura Abul-Husn M.D. Ph.D

Today, I’m joined by the incredible Dr. Nora Abdul-Hussein, a physician-scientist, medical geneticist, and one of the leading voices in the field of genomic medicine. In this episode, Dr. Abdul-Hussein and I dig into a huge question—why do two people taking the exact same GLP-1 medication have such wildly different results, from weight loss to side effect profiles? She shares her unique path from internal medicine to cutting-edge population genomics, and how her work at 23andMe is beginning to answer some of medicine’s toughest puzzles.

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GLP-1s & Peptides, Weight Loss, Genetics & GenomicsLorenz Ralph GañoGLP-1 medications, weight loss, pharmacogenomics, genetic variants, personalized medicine, genetic predisposition, type 2 diabetes, nausea and vomiting, side effects, GLP-1 receptor gene, GIP receptor gene, semaglutide, tirzepatide, genome-wide association study, pharmacogenetics, polygenic risk score, genetic ancestry, healthspan, longevity, metabolic health, prevention, biomarkers, ancestry testing, 23andMe, personalized interventions, clinical trials, obesity stigma, actionable genes, newborn sequencing, data privacy