Posts tagged personalized interventions
#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why “Healthy Sedentary” Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon
#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why “Healthy Sedentary” Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon

Today, I’m joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a “healthy sedentary person” and reveals the major role of intramuscular fat in metabolic dysfunction.

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Muscle & Strength, Aging & PreventionLorenz Ralph Gañomuscle quality, longevity, intramuscular fat, metabolic dysfunction, physical activity, brain health, inflammation, peptides, bioregulators, personalized interventions, skeletal muscle, resistance training, protein intake, plant vs animal protein, essential amino acids, GLP-1 medications, sarcopenic obesity, muscle as an endocrine organ, myokines, mitochondrial function, muscle loss with aging, anabolic agents, muscle gene therapy, satellite cells, childhood exercise, recovery and rest, muscle imaging, body composition, neuroprotection, strength training benefits
#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff
#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff

Today, I’m joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal “aha” moments that led her to champion true weight health, not just weight loss.

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Weight Loss, Nutrition & DietLorenz Ralph GañoGLP1 agonists, weight health, personalized nutrition, digestion, microbiome, peptides, bioregulators, autophagy, spermidine, nutrition coaching, insulin resistance, bariatric surgery, mental health, blood sugar, inflammation, dietary supplements, fiber, protein intake, hydration, personalized interventions, digestive enzymes, magnesium, supplementation, satiety hormones, weight loss medications, ancestral health practices, hormone replacement therapy, coaching for longevity, muscle vs. fat, healthspan optimization
#399:Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam
#399:Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam

Today, I’m joined by a lineup of trailblazers in the science of longevity: Ben Azadi, Dr. Teo Soleymani, Dr. Carrie Jones, Ian White, Dr. Robert Lufkin, and Dr. Jenn Simmons . Together we dig into some of the most persistent myths and cutting-edge research shaping how we age—including why “eat less, move more” misses the mark, what really causes skin cancers, breast cancer screening risks, and the often-overlooked ripple effects of perimenopause.

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Biohacking and Longevity, RecapLorenz Ralph Gañolongevity, peptides, bioregulators, ancestral health practices, personalized interventions, high quality protein, protein powders, Clean Label Project, metabolic flexibility, calorie deficit, hormone health, cell inflammation, gut microbiome, Biggest Loser study, basal cell carcinoma, melanoma, squamous cell carcinoma, sun exposure, sunscreen ingredients, skin aging, perimenopause, menopause, estrogen decline, joint pain, hormone replacement therapy, metabolic health, breast cancer screening, DCIS (ductal carcinoma in situ), immune system, plasma exchange, parabiosis
#393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso
#393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso

Today, I'm joined by the incomparable Dr. Ted Achacoso—a true pioneer in shifting healthcare from “what’s wrong with you” to “what’s right with you.” Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can’t ignore, and how something as simple as a toxicity panel can completely change your health trajectory.

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Mitochondrial Health, Health OptimizationLorenz Ralph GañoLongevity, health optimization, peptides, bioregulators, cellular health, vitamin D, metabolomics, toxicity panel, nutrition, personalized interventions, immune system, sleep support, digestive health, supplements, biohacking, ancestral health, mitochondria, cell stress pathways, self injury response, doom scrolling, hormone balancing, calcium regulation, vitamin K, vitamin A, lifestyle medicine, nutritional medicine, chronic disease, sunlight exposure, behavioral change, inflammation
#382: Building Stronger Women from their 20s to their 70s: Hormones, Iron Testing, and Menopause Breakthroughs With Dr. Amy Killen
#382: Building Stronger Women from their 20s to their 70s: Hormones, Iron Testing, and Menopause Breakthroughs With Dr. Amy Killen

Today, I’m thrilled to welcome Dr. Amy Killen, a visionary in hormone optimization and regenerative medicine who is transforming the conversation around women’s health and longevity. In this episode, Dr. Killen shares her personal journey—from witnessing her mother’s struggle after a hip fracture, to becoming a steadfast advocate for correcting the myths and misinformation that still surround estrogen, progesterone, and testosterone optimization.

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Hormonal Health, Women's HealthLorenz Ralph Gañolongevity, hormone optimization, bioidentical hormones, testosterone for women, estrogen, progesterone, perimenopause, menopause, ferritin, iron levels, bone health, stem cell therapy, sexual health, libido, energy, sleep, sarcopenia, muscle mass, insulin sensitivity, thyroid, cortisol, SHBG (sex hormone binding globulin), HRT (hormone replacement therapy), NMN supplement, peptides, bioregulators, mitochondrial function, skin health, breast cancer risk, dietary protein, personalized interventions, gut health