Posts tagged oxidative stress
#421: Trauma SCIENCE: How Hidden Stress Hijacks Your Health (Autoimmunity, Brain Inflammation, and Unlocking Resilience) | With Dr. Aimie Apigian
#421: Trauma SCIENCE: How Hidden Stress Hijacks Your Health (Autoimmunity, Brain Inflammation, and Unlocking Resilience) | With Dr. Aimie Apigian

Today, I’m joined by Dr. Aimie Apigian, an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine—where symptom management was the norm—to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity.

Read More
Nervous System Health, Mitochondrial HealthLorenz Ralph Gañolongevity, trauma, nervous system, chronic stress, resilience, biological capacity, mitochondria, autoimmunity, brain inflammation, mold exposure, attachment patterns, immune system, gut health, functional medicine, somatic therapy, trauma therapy, survival state, vagus nerve, overwhelm, oxidative stress, telomeres, mitochondrial biogenesis, epigenetics, generational trauma, gut microbiome, nervous system tracking, sleep problems, hormesis, mitochondrial repair, self-regulation
#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana
#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana

Today, I’m joined by the extraordinary Dr. Natalie Yivgi-Ohana, a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind—Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age.

Read More
Mitochondrial Health, Aging & LongevityLorenz Ralph Gañomitochondria, mitochondrial dysfunction, energy production, ATP, stem cells, immune function, mitochondrial transfer, endosymbiotic theory, aging, chronic disease, fertility, hormone production, neurodegeneration, mitochondrial biomarkers, mitochondrial transplantation, metabolic flexibility, ketogenic diet, free fatty acids, glucose metabolism, mitophagy, mitochondrial biogenesis, placental mitochondria, Pearson syndrome, myelodysplastic syndrome (MDS), Coenzyme Q10, NAD, oxidative stress, senescent cells, stem cell exhaustion, regenerative medicine, emotional health
#416: The Cardiovascular Crisis No One Talks About: Women, Midlife & Nitric Oxide Explained With Cathy Eason
#416: The Cardiovascular Crisis No One Talks About: Women, Midlife & Nitric Oxide Explained With Cathy Eason

Today, I’m joined by the remarkable Cathy Eason, whose work in the nitric oxide and vascular health space is changing the conversation around resilience and heart health for midlife women. Cathy dives into why cardiovascular disease is still the number one threat to women globally, and how the drop in estrogen during menopause impacts nitric oxide production—an overlooked factor that quietly influences everything from energy to cognition.

Read More
Cardiovascular Health, Hormones & MenopauseLorenz Ralph Gañomenopause, cardiovascular health, nitric oxide, vascular health, estrogen decline, midlife women, heart disease, blood flow, resilience, mitochondria, longevity, blood pressure, nitric oxide production, immune dysfunction, perimenopause, hormone replacement therapy, symptoms of menopause, hot flashes, cognition, autophagy, blood sugar regulation, magnesium, sleep quality, oxidative stress, nutrition, blood vessels, wearable health tech, supplements, stress adaptation, recovery after exercise
#408: The Surprising Truth About Metabolomics, Stress, and Slowing Aging (Peptides, Heavy Metals & Foundational Health Secrets) With Gus Vickery
#408: The Surprising Truth About Metabolomics, Stress, and Slowing Aging (Peptides, Heavy Metals & Foundational Health Secrets) With Gus Vickery

Today, I’m sitting down with Dr. Gus Vickery, a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine.

Read More
Metabolic Health, Functional MedicineLorenz Ralph Gañolongevity, metabolomics testing, mitochondrial health, nutrient depletion, foundational supplements, personalized interventions, peptides, bioregulators, stress, sympathetic dominance, heart rate variability, oxidative stress, cell membrane health, NAD balance, glutathione support, essential fatty acids, phospholipids, B vitamins, magnesium, heavy metals, environmental toxicity, detox protocols, gut biome, toxin exposure, air and water filtration, sleep optimization, age-related testing, regenerative therapeutics, stress management, epigenetic age, supplementation strategies
#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore
#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

Today, I’m joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.

Read More
Longevity, BiohackingLorenz Ralph GañoLongevity, peptides, bioregulators, mitochondrial health, AMPK, mTOR, metabolic training, neural hypertrophy, tension-based hypertrophy, cellular medicine, muscle building, fat loss, autophagy, mitophagy, circadian rhythm, recovery strategies, nutrition, supplements, ketone monoester, NAD/NADH ratio, oxidative stress, phospholipids, plasmalogens, SS31 peptide, MOTS-c peptide, Humanin peptide, BAM15 molecule, SLU molecule, exercise mimetics, senescent cells, immune support
#389: How Migraines, Mitochondria Dysfunction, and Modern Lifestyles Impact Brain Health and Aging With Dr. Elena Gross
#389: How Migraines, Mitochondria Dysfunction, and Modern Lifestyles Impact Brain Health and Aging With Dr. Elena Gross

Today, I’m joined by the brilliant Dr. Elena Gross, a neuroscientist with an inspiring story and a relentless drive to solve the mysteries behind chronic migraines and brain health. Dr. Gross’s personal journey—enduring twenty days of migraine each month and navigating countless failed treatments—led her from crawling through the pain to founding Brain Ritual, a company reimagining brain fuel for longevity.

Read More
Brain Health, MigraineLorenz Ralph Gañochronic migraines, mitochondria, brain energy deficit, ketones, oxidative stress, migraine triggers, blood brain barrier, exogenous ketones, ketogenic diet, glucose metabolism, insulin resistance, aura phase, migraine diagnosis, neuropeptides, gut microbiome, antioxidants, micronutrients, trace minerals, electrolytes, melatonin, vitamin D3, bioidentical hormones, NAD+, mitochondrial dysfunction, Brain Ritual supplement, processed foods, toxins, perfumes, longevity, ancestral health practices, neuroinflammation