#412: From Anti-Aging to Age Reversal: The Exosome & Copper Peptide Breakthrough For Younger Skin With Debbi Barber and Dr. Jordan Plews
Today, I’ve got a conversation that goes deep into the cutting edge of regenerative skin health with two exceptional guests: Debbi Barber, founder and muse of Vitali Skincare, and Dr. Jordan Plews, a biochemical engineer and stem cell researcher. We discuss the science and practical realities of exosomes, stem cells, and copper peptides—breaking down not just what makes skin look younger, but what truly keeps it biologically healthier and more resilient as we age.
Debbi opens up about her personal journey from passionate skincare hobbyist to nearly 70-year-old founder of a brand that’s rewriting what’s possible for aging skin. Together with Dr. Plews, they reveal what’s really behind stem cell exhaustion, why exosome signaling is a game-changer, and how their partnership led to developing skin solutions that go far beyond surface beauty.
If you’re curious about how regenerative biology is transforming both the science and industry of skincare—or if you simply want to know what actually works as we get older—this episode will give you fresh insights, actionable advice, and a look at what the future holds for longevity in skin health.
https://www.vitaliskincare.com/?ref=Nat20 | Nat20
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Website: https://www.vitaliskincare.com/?ref=Nat20 (code Nat20)
What We Discuss:
Welcome and podcast purpose ... 00:00:00
Shift from beauty to science and health ... 00:09:23
GHK-Cu’s role in longevity and skin repair ... 00:10:15
Dr. Plews on regenerative medicine and stem cells ... 00:11:14
From peptides to exosomes: product evolution ... 00:13:35
Stem cell exhaustion and need for exosome signaling ... 00:14:07
Copper peptides vs. exosomes: complementary actions ... 00:18:00
Why source and age of exosomes matter ... 00:25:20
Quality, safety, and labeling in exosome products ... 00:35:01
How exosomes and peptides benefit skin deeper layers ... 00:44:35
Visible results: barrier, redness, scars, texture ... 00:58:05
What to expect: younger vs. older skin ... 01:00:01
Proof and stories: customer transformations ... 01:01:59
More isn’t better: exosome dosing myth ... 01:07:03
Supporting ingredients: vitamin C, glutathione, SOD2 ... 01:11:31
Skin as a window into systemic aging ... 01:19:08
The future: personalized, organ-targeted exosome therapies ... 01:24:02
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