#409: How to LIVE YOUNG for a Lifetime: The Real Secrets of Mindset, Medicine & Longevity | Personalized Health Explained With Dr. Jeffrey Gladden
Today, I’m joined by the inspiring Dr. Jeffrey Gladden—a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept “normal for your age” as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same.
In this conversation, we dig into why most conventional medicine still focuses on treating sickness instead of optimizing health. Dr. Gladden shares eye-opening insights about how insulin and nervous system stress silently accelerate aging, why the same diet can help one person yet harm another, and how asking the right questions—rather than getting married to answers—can truly transform your health span.
If you’re ready to move beyond settling for “fine” and instead create a resilient, personalized path to staying youthful in body and mind, this episode will empower you with practical strategies, fresh perspectives, and the mindset shifts needed for longevity that actually lasts.
Learn more from Dr. Jeffrey Gladden below:
Website: https://gladdenlongevity.com/
Book: 100 Is the New 30: How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime
Youtube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw
Instagram: https://www.instagram.com/gladdenlongevity
What We Discuss:
Welcome and episode introduction ... 00:00:00
Health crisis and discovering personal optimization ... 00:07:05
From “sick care” to health optimization ... 00:10:46
Vision for personalized, youthful longevity ... 00:12:17
Personalized medicine: why one size doesn’t fit all ... 00:16:00
Linear versus exponential aging; fixing a flawed approach ... 00:18:02
Five circles of exponential health: key longevity domains ... 00:19:23
Curiosity, growth mindset, and quantum thinking in longevity ... 00:22:22
Why individualization is crucial for diet and interventions ... 00:28:52
Insulin resistance: the hidden driver of aging ... 00:33:41
Environmental and internal (psychospiritual) factors in health ... 00:38:40
Healing through meditation, stress management, and flow ... 00:41:15
Robustness, resilience, and anti-fragility as longevity superpowers ... 00:57:09
Safe, personalized hormone therapy and the importance of tracking ... 01:03:33
Integrating mindset, purpose, and psycho-spiritual work ... 01:08:50
Peptides and advanced therapies: preparing for optimal results ... 01:09:56
Common test misconceptions in longevity medicine ... 01:12:56
Debunking the myth of single biological age ... 01:16:38
Resources, connect with Dr. Gladden, and closing ... 01:18:09
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