#482: He Treated 13,000 Complex Patients. What He Found Could Change Chronic Disease Medicine Forever | Dr. Richard Horowitz

Today, I’m joined by the extraordinary Dr. Richard Horowitz, a board-certified internist, renowned Lyme disease specialist, and the author of Ending Chronic Illness—a book that’s become my new favorite reference guide for understanding the true roots of chronic disease. Dr. Richard Horowitz opens up about his journey from treating diabetes in upstate New York to becoming a medical detective in the heart of the country’s largest Lyme-endemic area, where standard medical training simply wasn’t enough. Patient by patient, he pieced together a radical new model for uncovering where inflammation really comes from—one that’s now transforming lives well beyond Lyme.

#478: My FAVORITE Tool For Unlocking Daily Stress | Soothes You Right To Sleep Too! With Dr Dave Rabin, MD, PhD

Today, I’m joined by Dr. David Rabin, a triple-threat psychiatrist, neuroscientist, and author of A Simple Guide to Being Alive. In this episode, Dr. Rabin brings a refreshingly human perspective to one of life’s biggest questions: What does it really mean to be alive? We dive into why so many of us have been taught to treat our emotions as problems to fix, rather than signals to listen to, and explore the invisible cost of misunderstanding our own nervous systems.

#421: Trauma SCIENCE: How Hidden Stress Hijacks Your Health (Autoimmunity, Brain Inflammation, and Unlocking Resilience) | With Dr. Aimie Apigian

Today, I’m joined by Dr. Aimie Apigian, an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine—where symptom management was the norm—to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity.

#397: STRESS: The Silent Accelerator of Aging (10 Free Hacks Rewiring Your Longevity) | Calm Amid Chaos With Nat Niddam

Today, it’s just me, and we’re doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives and high-tech hacks to focus on something fundamental—free, practical strategies to help you manage stress. Chronic stress is sneaky in how it accelerates aging, impacts your telomeres, and undoes even the most powerful interventions, but thankfully, there are simple ways we can start to turn things around.

#392: Biohacking the MIND: 78% Anxiety Remission, Vagus Nerve Secrets & The Mental Health Revolution | Zenbud’s Jon Hacker Unlocks REST

Today, I’m joined by the innovative Jon Hacker, whose name couldn’t be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mind. After growing up with severe OCD and witnessing the rising tide of global anxiety, he became obsessed with one question: Why are we all stuck in fight or flight, and what can we actually do about it?

#379: The NEW Biohacking Stack For Gut Healing and Lifelong Vitality | Kiran Krishnan & Forrest Smith

Today, I’m sitting down with two true pioneers in the health optimization space: microbiologist Kiran Krishnan from Just Thrive, and Forrest Smith, founder of Kineon. In this episode, we bridge two often separate worlds—gut health and photobiomodulation—to explore what happens when you combine spore-based probiotics with red and near-infrared light therapy. You'll hear about the unexpected links between the gut and brain, the pivotal role of leaky gut in everything from neurodegeneration to hormone imbalance, and why Forrest started experimenting with shining red light directly on his abdomen.

#371: Fix Chronic Body Pain For Good: The Shocking Link Between Feet, Jaw, Eyes & Longevity (Neuroscience Secrets REVEALED!) | Annette Verpillot

Today, I’m joined by Annette Verpillot, the visionary founder of Posture Pro, whose work is transforming how we think about alignment, movement, and brain health. Annette shares her groundbreaking brain-first approach to posture, revealing how the real root of tension, pain, and subpar movement lies not just in your muscles or bones, but deep within your nervous system. In our conversation, Annette takes us behind the scenes of her “three-legged stool” model—where your feet, eyes, and jaw work together as the true command center for posture and performance.

Covering the latest research directly from the experts across peptides, epigenetics, actionable biohacking, data-driven healthtech & more.

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