Today, I’m joined by the thoughtful Dr. Clement Lee, a naturopathic doctor blending ancient wisdom from Chinese medicine with cutting-edge regenerative therapies. In this episode, Dr. Lee gets real about why people can feel deeply unwell long before anything shows up on standard labs—and how subtle issues like limbic system stress, toxins, and chronic inflammation quietly undermine our vitality.
Read MoreToday, I’ve got a conversation that goes deep into the cutting edge of regenerative skin health with two exceptional guests: Debbi Barber, founder and muse of Vitali Skincare, and Dr. Jordan Plews, a biochemical engineer and stem cell researcher. We discuss the science and practical realities of exosomes, stem cells, and copper peptides—breaking down not just what makes skin look younger, but what truly keeps it biologically healthier and more resilient as we age.
Read MoreToday, I’m joined by Dr. Stephen Hussey—a clinician, author of Understanding The Heart, and a powerful force in rethinking everything we thought we knew about heart disease. Dr. Hussey’s own journey began with type 1 diabetes as a child, and despite living a healthy, active lifestyle, he experienced a widowmaker heart attack at just 34 years old. In our conversation, he opens up about what it was like to face this crisis with “perfect” lab numbers, how it challenged his entire perspective, and ultimately led him to a radical new understanding of heart health and longevity.
Read MoreToday, I’m joined by the wonderful Dr. Shivani Gupta, a true force in bridging ancient Ayurvedic wisdom with cutting-edge modern research on inflammation and healthy aging. She recently authored The Inflammation Code. Dr. Shivani opens up about her deeply personal motivation—from witnessing her grandfather’s preventable health decline to spending years in both traditional and scientific studies, ultimately earning a PhD focused on turmeric and chronic inflammation.
Read MoreToday, I’m joined by the inspiring Dr. Jeffrey Gladden—a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept “normal for your age” as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same.
Read MoreToday, I’m sitting down with Dr. Gus Vickery, a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine.
Read MoreToday, I’m joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a “healthy sedentary person” and reveals the major role of intramuscular fat in metabolic dysfunction.
Read MoreToday, I’m joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.
Read MoreToday, I’m joined by the deeply thoughtful and refreshingly honest Dr. Sanjay Bhojraj, a self-described “curious cardiologist” who spent decades treating heart attacks in the cath lab — before stepping away to ask a bigger question: Why are we waiting for the crisis instead of preventing it?
Read MoreToday, I’m joined by Charles Bohdy, a true innovator in water purification technology, and Victor Sagalovsky, a passionate advocate for bringing the science of water quality into our daily lives. Together, we take a deep dive into the unseen world of the water running through our homes—exploring not just its purity, but its hidden potential to support our biology in ways most of us have never considered.
Read MoreToday, I’m joined by Ben Katz—better known online as Mr. Mass Spec —an academic analytical chemist from UC Irvine whose mission is to uncover what’s really in our everyday foods, drinks, and products. Ben reverse engineers everything from Taco Bell meat to Doritos, and sometimes even entire industries, using cutting-edge mass spectrometry. His curiosity and expertise have made him a go-to source for those wanting to know what’s hiding behind vague ingredient labels and “natural flavors.”
Read MoreToday, I’m kicking off the new year with a back-to-basics deep dive into one of the most pivotal yet overlooked foundations of longevity: gut health. Over the past episodes, we’ve explored everything from gene therapy to advanced tech, but it all comes back to the habits and systems we rely on every single day—and the gut is right at the center of that equation.
Read MoreToday, I’m joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal “aha” moments that led her to champion true weight health, not just weight loss.
Read MoreToday, I’m excited to bring back the always thought-provoking Joel Greene, author of “The Immunity Code” and “The Way,” for a fresh conversation on why true longevity is about so much more than how much muscle you have or the latest diet trend you’re following. Joel Greene opens up about the hard lessons he’s learned from decades of self-experimentation and reveals why chasing that ideal gym physique might actually backfire as you age.
Read MoreToday, I’m joined by a lineup of trailblazers in the science of longevity: Ben Azadi, Dr. Teo Soleymani, Dr. Carrie Jones, Ian White, Dr. Robert Lufkin, and Dr. Jenn Simmons . Together we dig into some of the most persistent myths and cutting-edge research shaping how we age—including why “eat less, move more” misses the mark, what really causes skin cancers, breast cancer screening risks, and the often-overlooked ripple effects of perimenopause.
Read MoreToday, I’m joined by Lucas Aoun, from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father’s pharmacy, to experimenting with early nootropic formulas, and ultimately becoming a sought-after educator in the world of biohacking.
Today, it’s just me, and we’re doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives and high-tech hacks to focus on something fundamental—free, practical strategies to help you manage stress. Chronic stress is sneaky in how it accelerates aging, impacts your telomeres, and undoes even the most powerful interventions, but thankfully, there are simple ways we can start to turn things around.
Read MoreToday, I’m joined by Dr. James Hardt—founder of Biocybernaut and a true pioneer in the world of neurofeedback. With over four decades spent mapping how our brainwaves shape emotions, performance, and even identity, Dr. Hardt has helped reframe the conversation around unlocking human potential, making cutting-edge brain training accessible to seekers, creatives, and everyday biohackers alike.
Read MoreToday, I’m sitting down with the irrepressible Siggi Clavien, renowned biotech innovator and founder of De-liver-ance, a groundbreaking formula for liver health. Siggi’s story is deeply personal—motivated by the loss of loved ones to liver disease, he’s made it his life’s mission to demystify liver health and help others avoid the fate that touched his own family.
Read MoreToday, I’m joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly with Professor Vladimir Khavinson—the scientist who discovered and developed bioregulator peptides—and has spent the last eight years leading some of the most exciting field research in this space.
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